Skeleton
You should use Skeleton if you're embarking on a smaller project or just don't feel like you need all the utility of larger frameworks. Skeleton only styles a handful of standard HTML elements and includes a grid, but that's often more than enough to get started. In fact, this site is built on Skeleton and has ~200 lines of custom CSS (half of which is the docking navigation).
Alternatives to Skeleton
Foundation
Free
Description Foundation Software is a platform for construction accounting that is ideal for commercial, prevailing wage, government, and industrial contractors. The software developer
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Bootstrap
Free
Bootstrap is one of the most popular and frequently used front end frameworks in use today.
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Materialize
Free
Materialize is a framework enabling developers to apply Google's Material Design guidelines to quickly develop websites that provide users with an intuitive interface and the functionality
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Semantic UI
Free
Semantic empowers designers and developers by creating a shared vocabulary for UI.
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UIKit
Free
UIkit, a lightweight and modular front-end framework for developing fast and powerful web interfaces.
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Bulma
Free
Bulma is a free, open source CSS framework based on Flexbox and built with Sass. It's 100% responsive, fully modular, and available for free.
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Mini.css
Free
Mini.css is a tiny CSS framework designed to build quick, modern and responsive websites.
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Galaxy
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Topcoat
Free
TopCoat, TopWeb, Rheologic, Software for coating, drying, converting, web handling, industries.
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Spectre.css
Free
Spectre.css CSS Framework is a lightweight, responsive and modern CSS framework for faster and extensible development. Spectre provides basic styles for typography and elements, flexbox
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PostCSS
Free
Increase code readability. Add vendor prefixes to CSS rules using values from Can I Use. Autoprefixer will use the data based on current browser popularity and property support to apply prefixes
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Blueprint
Free
The official homepage for Blueprint, the original CSS framework. Also known as Blueprint CSS.
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